SigED is used to compute three Z-scores, SigZscre(Si), SigSteme(Si), and SigLoope(Si), of local segments in a sequence. These scores can be computed by sliding a fixed-length window in steps of a few nucleotides from 5' to 3' along the searched sequence. It is often used in a particular interested region that was previously determined by the more rapid method, edscan. The maximum sequence length is allowed upto 4995000 bp. In general the moving step size is 3-5 bp and segment (window) length is less than 300 bp.
The program SigED package (SigED.tar) includes a Readme file and files listed below:
1. Source Codes for SigED:
siged.f tematf.f trace.f cfd.inc 2. Energy Table Files for SigED:
turner.tbl (Turner energy rules for RNA folding) It can be easily compiled by
f90 -o SigED -O3 -extend_source siged.f tematf.f trace.f 3. A test job file: SigED.csh
4. An input sequence file: eleg.seq
5.An input control file: W75.in
6. An output file: eleg_W75.zscr